| 1452 | Leonardo da Vinci is born. | ||
|---|---|---|---|
| 1455 | Johannes Gutenberg completes printing the Bible in Mainz using movable type | ||
| 1469 | Desiderus Erasmus is born. | ||
| 1473 | Nicolaus Copernicus is born. | ||
| 1475 | Michelangelo is born. | ||
| 1485 | Thomas Cromwell probably born. | ||
| 1492 | Columbus sets sail for the Americas. | ||
| 1493 | Maximilian I becomes Holy Roman Emperor. | ||
| 1500 | Charles V is born. | ||
| 1509 | Erasmus writes In Praise of Folly. | ||
| 1513 | Battle of the Spurs: Henry VIII's forces defeat the French, at Guinegate. | ||
| 1515 | Battle of Marignano. | ||
| 1516 | Erasmus' Greek New Testament published. | ||
| 1519 | Charles V elected as Holy Roman Emperor. | ||
| 1519 | Maximillian I dies. | ||
| 1522 | Fall of the Aztecs to Cortes. | ||
| 1524 | Erasmus writes On the Freedom of the Will. | ||
| 1524 | May 30 | Peasants in the Black Forest region of Germany begin Peasants' War. | Peasants' War |
| 1526 | Charles V marries Princess Isabella of Portugal. | ||
| 1526 | August 29 | Battle of Moh?cs. | Battle of Mohács |
| 1529 | The Turks attack Vienna. | ||
| 1533 | Fall of Incas to Pizarro. | ||
| 1533 | The Buggery Act is adopted by Henry VIII. | The Buggery Act | |
| 1536 | Thomas Cromwell secures the Act of Dissolution which closes monasteries. | ||
| 1540 | July 28 | Henry VIII has Thomas Cromwell executed. | |
| 1550 | Bartolome de Las Casas writes In Defense of the Indians. | ||
| 1552 | Bartolome de Las Casas writes The Brief Account of the Destruction of the Indes. | ||
| 1553 | Constantinople falls to the Turks. | ||
| 1558 | Charles V dies. |